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One easy-to-follow guideline that incorporates each of these facets is the Mediterranean diet, which is packed with fruits, vegetables, whole grains, and healthy fats

Another was the discovery that tight junctional permeability is dynamic, altered by systemic inflammation and other factors such as enterotoxins and the volume of fluid absorption [23, 39], initially reported in the early 1980s in clinical studies of intestinal permeability in arthritis and celiac disease patients [37, 40]