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The biggest risk is the lack of safety evidence

Front Aging Neurosci

Meaningful GLP-1 receptor activation for appetite suppression typically begins around 0.5mg to 1.0mg, though individual responses vary

Tralokinumab-ldrm and nemolizumab can cause other side effects like upper respiratory tract infections (such as the common cold) and high levels of eosinophils (a type of white blood cell)