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The reactions in these pathways are of particular interest in medicine as part of drug metabolism and as a factor contributing to multidrug resistance in infectious diseases and cancer chemotherapy

Standardized Tests (02:16:40) Mindset Research (02:23:53) Zero-Cost Support, Spotify & Apple Reviews, Sponsors, YouTube Feedback, Momentous, Social Media, Neural Network Newsletter Disclaimer Day 184 GUEST SERIES | Dr

NVU Neurovascular unit (endothelial cells, astrocytes, pericytes, ECM and neurons) OGD Oxygen and glucose deprivation (to mimic ischemia) P-gp P-glycoprotein TEER Transendothelial electrical resistance (TEER) TJs Tight junction proteins

The classical metastatic cascade starts from a primary, epithelial, neoplastic lesion and includes: (1) epithelial mesenchymal transition (EMT) with a breach of the basement membrane barrier