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110, 111 Extracellular ATP has recently been discovered as a potent danger signal for DCs, triggering purinergic receptor on airway DCs and leading to a DC-dependent allergic sensitization toward the co-inhaled inert protein

Two slim women smoking cigarettes on parking lot next to club, girltime break Captions are provided by our contributors

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However, in a recent randomized controlled trial of 300 smokers [58], only 26.9% of those who switched to e-cigs resulting in complete smoking abstinence were still using the product by the end of the observational period (week-52) with the 73.1% of users stopping vaping as well