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Purine pathway implicated in mechanism of resistance to aspirin therapy: pharmacometabolomics-informed pharmacogenomics

The result is greater bioavailability and more reliable clinical response in a convenient, single-dose oral format

Briefly, cells were added to 96-well plates (5 10 3 )/well and incubated in the presence of a range of PQQ concentrations (1, 5, 10, 25, 50, 100, 150, 200 M), with six replicate samples per condition

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