Research investigations in aging tissue models demonstrate remarkable improvements across multiple cellular parameters
Clin Cancer Res 11 : 49124922 Munster P, Marchion D, Bicaku E, Schmitt M, Lee JH, DeConti R, Simon G, Fishman M, Minton S, Garrett C, Chiappori A, Lush R, Sullivan D, Daud A (2007) Phase I trial of histone deacetylase inhibition by valproic acid followed by the topoisomerase II inhibitor epirubicin in advanced solid tumors: a clinical and translational study
G1-S transition is critical for cell cycle progression, and DKK1 notably reduced morroniside-mediated cell proliferation and decreased G1/S transition
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