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Guan Y, Wang SR, Huang XZ, Xie QH, Xu YY, Shang D, Hao CM (2017) Nicotinamide mononucleotide, an NAD+ precursor, rescues age-associated susceptibility to AKI in a sirtuin 1dependent manner

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This protective effect was further validated during parthenogenetic activation, where aged oocytes displayed a fragmentation rate reduction of approximately 27% following Epitalon treatment