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10.1016/j.immuni.2017.03.022 52 KumarA.SidhuJ.LuiF.TsaoJ

Results Cystine availability regulates mTORC1 signaling and the ISR We studied the effect of cystine starvation in HepG2 cells, which do not synthesize cysteine from methionine, to exclude the confounding effect of methionine 20

Intestinal Barrier Dysfunction: Preclinical evidence suggests that by lowering systemic oxidative stress, NAC may promote intestinal barrier integrity and support a healthy balance of intestinal microbiota, addressing the gut dysbiosis often seen in chronic illness