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The peptide therapys mechanism of action involves the potentiation of hepatocyte growth factor (HGF) and its receptor, c-Met, which plays a crucial role in synaptic plasticity and neurotrophic support

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The dermal stem cell factor and c-kit are overexpressed in melasma

Ralph RJ, Paulus MP, Fumagalli F et al (2001) Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: differential effects of D1 and D2 receptor antagonists