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Prevalence varies substantially by ancestry null frequencies reach 5060% in some East Asian populations and are approximately 2030% in African-ancestry populations in most published frequency estimates

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Evidence Integration Overall, considering the available evidence from human, animal, and mechanistic studies, evidence indicates that exposure to jet fuels is likely to cause neurotoxicity in humans under relevant exposure circumstances (Table 1 and Supplemental Digital Content, Supplementary Table S9, This conclusion is based primarily on evidence of hearing impairment or abnormal auditory processing in both epidemiologic and animal toxicological studies

Although the protective effect of glycine on MIR injury has also been investigated, whether it can augment the level of GSH in the ischemiareperfusion (I/R) myocardium is unclear