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Furthermore, periosteum bone formation rate and mineralizing surface also appeared to be preserved and several-fold higher than in catabolic agent-only models, partially restoring the suppressed bone formation

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doi: 10.1016/j.jbspin.2025.105892 Summary Keywords NLRP3 inflammasome, oxidative stress, programmed cell death, sodium urate crystal, soluble uric acid Citation Yang Q, Xu Y, Zhang J, Xiao N, Lu H, Chen B, Yang B, Xie Z and Li Z (2026) From soluble uric acid to sodium urate crystal: immune metabolic inflammation driven by uric acid morphological transformation and mechanism-oriented therapy