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Pickart estimated the toxic dose at approximately 22,500 mg, which is over 11,000 times the recommended daily dose

Expression of SBP2 , a factor recognizing SECIS element, had a positive correlation with GPX1 and GPX4 expression and antioxidant capacity in chondrocytes 96

To investigate the drug-likeness features of the seven lead compounds identified herein, predicted ADMET parameters were determined using pkCSM (Supplementary Table S6)