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Description

IGF-1 and IGFBP-3 were measured at baseline, Year-1 and Year-3

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Given the low K Mof GR for NADPH (Smith et al., 1989

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Cellular thiols, hydroquinones and catecholamines can undergo redox reactions and contribute to intracellular ROS production as well

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showed that IGF1 LR3 had about 100-fold lower affinity for IGFBP-3 compared to native IGF-1, while retaining similar receptor binding characteristics

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