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[9] Visual disturbances have been reported in patients with Leber hereditary optic neuropathy, and rapid B12 administration may precipitate optic nerve atrophy in this genetically predisposed population, mandating extreme caution or alternative therapy

10.1093/ajcn/nqaa221 18 DoetsE

AOD9604 is used in non-clinical laboratory research involving adipose-related pathways, metabolic regulation models, and synthetic peptide fragment studies under controlled experimental conditions

The affinity of the GHK tripeptide for copper is exceptionally high, and it is this complex that is believed to be the primary biologically active form