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The safety assessment is based on the independent safety profiles of each compound (GLP-1 medications through extensive FDA trials, BPC-157 through decades of preclinical research), their non-overlapping mechanisms, and growing clinical experience from physicians who prescribe both

More severe or persistent sinus infections are usually treated with antibiotics

Pancreatitis Sudden inflammation of the pancreas (an organ that helps with digestion and blood sugar regulation) can occur, although it is rare and has been reported in 13 patients taking tirzepatide

Similarly, a study of Reddit users' self-reported side effects of retatrutide differed markedly from clinical trial data, including increased appetite, food cravings, and insomnia