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Extracellular matrix regulation in connective-tissue models. J Invest Dermatol

Specifically, eligible studies included participants (P) with a confirmed diagnosis of vitamin B12 deficiency, interventions (I) involving oral or sublingual vitamin B12 administration, comparators (C) using intramuscular supplementation, and outcomes (O) reporting changes in serum vitamin B12 or homocysteine levels

Once in the bloodstream, B12 contributes to: For many clients, noticeable improvements in energy and mental sharpness occur within hours to a few days after the injection

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