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van de Rest O, van Hooijdonk LW, Doets E, et al

A major disadvantage of using Drosophila to investigate human diseases is the difference between the brain anatomy of flies and that of humans

Intriguingly, the rs1063843 polymorphism that is associated with bipolar disorder and reduced CAMKK2 mRNA expression in the human brain, is also associated with functional impairment of the caudate nucleus [153]