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VGLUT1 glutamatergic presynaptic marker Synapsin Fereira and Rapoport 2002 PSD-95 the postsynaptic marker Nle1-AngIV and Dihexa increase miniature synaptic activity by increasing dendritic spine densities and altering the morphological phenotype of postsynaptic spines in-vitro and may represent the mechanism that underlies facilitated learning observed AngIV analogues (Wright, Stubley et al

The primary mechanism of AOD-9604 in laboratory research models is selective beta-3 adrenergic receptor (beta-3 AR) activation