I know at least I sort of fall into pieces of that myself
This approach honors and acknowledges that inflammation and oxidative stress are at the core of the pathophysiology of the patients pain
doi:10.1074/jbc.M110.189944, PMID: 21037289 Kamide Y, Utsugi M, Dobashi K, Ono A, Ishizuka T, Hisada T, Koga Y, Uno K, Hamuro J, Mori M (2011) Intracellular glutathione redox status in human dendritic cells regulates IL-27 production and T-cell polarization
Last, the mRNA expression of genes encoding scaffolding ( PSD-95 ), transcription regulation proteins ( MeCP2, CaMKII ), the subunits of NMDA ( NR1, NR2a , and NR2b ) and AMPA ( GLUR1 and GLUR2 ) receptors, as well as the metabotropic glutamate receptors mGLUR1 and mGLUR5 , that are all involved in the regulation of the post-synaptic terminal activity, was evaluated in the same brain regions