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Sublingual administration, which bypasses the gastrointestinal tract, appears to be equally effective as IM injections while being less invasive and more cost-efficientparticularly in patients with atrophic gastritis, post-gastrectomy status, or conditions that impair intrinsic factor-mediated absorption, where long-term intervention is often required

Selected Preclinical Data Study 1: Genetic Proof-of-Concept A seminal investigation reported elevated NNMT expression in white adipose tissue (WAT) and liver of obese/diabetic mice

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