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Cognition and memory also decline with age, and they have been correlated to low IGF-I levels as well[346349], through a proposed mechanism that may include its role in angiogenesis and neurogenesis in the hippocampus

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DeBerardinis (Children's Research Institute at University of Texas Southwestern, Dallas, USA) and J

With site-directed mutagenesis, four Q residues in the GST tag were identified as polyamination sites