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In SG broilers, three proteins were classified as exclusive, including cornulin (CRNN), which was significantly regulated by enrichment and exhibited lower expression in enriched environments

Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimers disease

Inflammatory cell infiltration follows tissue injury, initially serving protective functions but potentially causing secondary damage if prolonged or excessive

Thus, iron overload is inferred to cause bone damage by promoting osteoclast activity while simultaneously suppressing the formation of osteoblasts