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Description

directly reprogramed MEFs into iHeps with one step chemical induction consisting of SB431542, CHIR99021, BIX01294 (G9a KMT inhibitor), LDN193189, and DAPT (Zhong et al., 2024)

It has undergone numerous human clinical trials (Phase I/II) but has not pursued further regulatory development

What changed in this update 1) Standardized naming and synonym control Umbrella Labs standardized the primary naming convention as dihexa peptide across internal records and outward-facing reference language