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Probiotics as Lactocaseibacillus rhamnosus zz-1 can enhance tight junction protein expression (including ZO-1, occludin, and claudin-1) and promote epithelial barrier repair, thus limiting antigenic load and reducing systemic inflammation (Xu et al., 2023)

Rapid weight loss, extended undernutrition or extreme calorie reduction can stop typical steroidogenesis and cause follicle pools to diminish and eggs to fail to mature