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doi: 10.1016/j.neuron.2014.07.014 114 MaasD

IL-6, aside from its proinflammatory cytokine activity, may also cause an increase in BBB permeability, contributing to its disruption and further immune cell infiltration in CNS (93)

The brain sequesters glycine in concentrations of 600 M [14], with a basal concentration in the cerebrospinal fluid (CSF) of ~6 M [15], compared to a plasma concentration of ~250 M [16]