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The discontinuation was driven by (Bergam, 2025) (Figure 2): the availability of newer, safer & more accurate alternative testing for MG including electrophysiological & antibody tests, as well as safety concerns (bradycardia & respiratory complications) limited diagnostic reliability (with both false-positive and false-negative results) The decision to remove edrophonium as an available (alternative) diagnostic test has been challenged (Keritam et al, 2026)

10.1038/s41598-023-50604-4 101 SahaS

Biomaterials 34 (38), 1019910208

While we propose a model involving glycolysis and the TCA cycles, further measurement, for example, direct measurements of ETC activity in isolated mitochondria or markers of cell cycle could be carried out to compile further evidence