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These interventions aim to restore intestinal microecological balance, increasingly recognized as pivotal in the pathophysiology of these conditions

Both rheumatoid arthritis (an autoimmune condition) and osteoarthritis (degenerative joint disease) involve inflammation as a central driver of symptoms and progression

Methods Plant materials and growth condition hairpin RNA-52 (hr-52) was obtained from the rolling circle amplification-mediated hairpin RNA (RMHR)-based Arabidopsis library in our previous study 19,20