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This damage can result in mutations within oncogenes such as RAS and MYC, as well as tumor suppressor genes like p53 and PTEN, thereby fostering genomic instability and malignant transformation [31, 32]

Your own experience might move a little faster or slower that's normal, not a sign anything is wrong

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Another part of BA escapes from intestinal reabsorption, enters the colon, and gives rise to secondary BA by the resident gut microbiota ( Recent studies unequivocally pointed out that bile is not simply a fat emulsifier