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To receive a PMTA order, the application must demonstrate that the product is "appropriate for the protection of public health." 56 This determination is made based on the risks and benefits to the whole population of users and nonusers of the product, while taking into account the increased or decreased likelihood that existing users of tobacco products will stop using such products

[438] Letter from Goodale, Annex 1, p

Most e-cigarette starter kits feature an airflow design that closely replicates the inhale of a cigarette, to feel familiar to those making the switch from smoking

By the 1960s, tobacco companies began capitalizing on a growing womens movement by marketing cigarettes with slogans like Its a woman thing and Youve come a long way, baby. Some brands introduced cigarettes marketed exclusively for women like Virginia Slims, Eve, Misty and Capri