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Similar concerns apply to other supplements, including melatonin, where long-term safety remains an area of active investigation

have shown that inhibition of PSC activation is associated with a decrease in islet fibrosis and an increase in insulin secretion [35], indicating the potential role of PSC activation in -cell failure

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Contrarily to the other methods listed before, vaccine-based approaches do not only aim to target senescent cells in tissues, but also senescent immune cells, which can be responsible for age-related diseases 60