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Consistent with previous studies, our study found that the proportion of adenocarcinoma in both smokers and non-smokers showed a rapid upward trend, and the increasing rise in non-smokers with LC was even greater than in smokers (Supplementary file Figure 2), indicating that the change of smoking status now may not be the main factor affecting the change of LC pathological types

With only limited availability of HNB products, it is likely that many of those respondents were mistaken, answering yes to the HNB question when they meant e-cigarettes or vapor products

Successive governments have increased taxation on cigarettes and related products the so-called tobacco escalator for at least two decades in a bid to reduce consumption