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A third study found reduced glutamate in the occipital cortex in schizophrenia patients compared to healthy controls [42]

Prehepatic hyperbilirubinemia, results from excess production of bilirubin caused by hemolysis, or a genetic abnormality in the hepatic uptake of unconjugated bilirubin Hemolysis is usually the result of immune disease, presence of structurally abnormal red cells or breakdown of extravasated blood

This daily protocol was maintained for 7 consecutive days, after which cognitive testing demonstrated significant improvements in Morris water maze performance compared to vehicle controls

The substantial Phase I loading dose aims to minimize this translational failure for TB-500