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Glutathione and Vitamin C are anti-oxidants which prevent skin damage due to environmental stressGlutathione stimulate collagen and reduce fine lines and wrinkles

While the role of endogenous ROS as hormetic agents is emphasized in the above discussion, the same conclusion cannot be confidentially withdrawn in case ROS originated from exogenous sources, which might be the field of interest for further research

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Blood oxygen saturation (SaO2), blood gas, inflammatory factors, tissue water content, and pathological sections are commonly used to evaluate the success of the animal model (Wang et al., 2018