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Escherichia coli, Streptococcus faecalis, Clostridium difficile and certain Salmonella species can bind Se from the body to their own enzymes to use amino acids instead of thiamine-containing amino acids, and can also convert the soluble form of Se to an insoluble form, making it unavailable for absorption by the body (114)

And overall my goal was not to do anything and just enhance the body's own ability to to defend itself

Intriguingly, these inclusions were detected within brain regions described to be affected by neurodegeneration but also in regions that are typically spared in this disease [23,24,25]

This supplement helps make up for that loss