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TB-500, a synthetic fragment derived from thymosin beta-4, interacts with actin-associated cellular machinery that regulates cytoskeletal structure and cell migration

It is prepared by a U.S.-registered compounding pharmacy for individual patients based on a valid prescription, and its components are classified by the FDA as bulk drug substances under section 503A of the Federal Food, Drug, and Cosmetic Act

The specific requirements for any research protocol depend on the compound being evaluated and established laboratory procedures

For this purpose, the adjunctive therapeutic use of small molecules that either inhibit or stimulate eryptosis could represent a valid strategy for the treatment or prevention of pathological complications associated with erythrocyte dysfunction