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Here is a great thread we found from Layne Norton, a guy we interviewed over ten years ago whose interview is still well worth a read

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Endogenous and exogenous reactive oxygen species, such as superoxide anion, hydroxyl radical, hypohalite radical, and hydrogen peroxide, and reactive nitrogen species, such as nitric oxide, peroxynitrite, and nitrite, play a major role in the airway inflammation and are determinants of asthma severity

Woodworth MH, Conrad RE, Haldopoulos M, Pouch SM, Babiker A, Mehta AK