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In the study population, the researchers noted: While the risk of death and suicide attempts is lower during and shortly after pregnancy than in the general female population, suicides account for up to 20% of all postpartum deaths and represent a leading cause of mortality in the peripartum period, which corroborates the high prevalence of suicide risk in our sample of women. Based on growing evidence linking oxidative damage with neurodegenerative changes associated psychiatric disorders, as well as the intrinsic oxidative vulnerability of the brain, the study set out to evaluate the serum levels of oxidative stress biomarkers in women at risk of suicide after 18 months of postpartum

doi: 10.1371/journal.ppat.1008470 4 YangSLianG

Selenium-SelK-GPX4 axis protects nucleus pulposus cells against mechanical overloading-induced ferroptosis and attenuates senescence of intervertebral disc