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Hives can be caused by an allergic reaction to certain foods and nutritional supplements Hives occur when histamine, a chemical produced by your immune system, is released

The || cutoff was used to prioritize changes more likely to be biologically meaningful and is commonly adopted in array-based methylation studies

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The IGF-1 axis benefits from the same pause: it drifts back toward baseline instead of sitting chronically elevated, which is the safer position given GH/IGF-1s growth-promoting signaling