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OCN is a small c-carboxyglutamate protein, which is synthesized only by mature cementoblasts, osteoblasts and odontoblasts, and its function is controlled by RUNX2 in the later-stage of mineralized tissues 35,36,37

While subcutaneous injections are generally well tolerated, some patients experience mild to moderate localized reactions at the injection site

Because the mechanism is appetite-based rather than metabolically suppressive, muscle preservation tends to be strong when paired with adequate protein and resistance training, which matters for sustaining results

Dasari A, Gao H, Deaton L, Overman MJ, Hauch S, Kopetz S , Reuben, JM