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Subsequently, sequence similarity was assessed using BLAST tool, and a phylogenetic tree was constructed using the neighbor-joining method in Mega 7.0 software according to 16S rRNA gene sequences from 17 Lactobacillus strains

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This study revealed a distinct neurodevelopmental phenotype in the DS brain, characterized by a thicker cortical ribbon, particularly in the frontal and occipital lobes, and a thinner motor cortex