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AEDG) used in controlled in-vitro research to explore telomere biology pathways, cellular senescence markers, and circadian-related peptide signalling under non-clinical conditions

It is more common for results to be low, although pituitary tumors (sometimes leading to gigantism or acromegaly) can produce unusual results

The translational value of targeting cuproptosis and copper metabolism lies in the identification of key regulatory molecules (e.g., FDX1, DLAT, ATP7A/B) and potential biomarkers (e.g., serum CP and NCC) that could guide clinical decision-making